Dynal is the world-leading provider of biomagnetic separation technology. Moving into areas that increasingly impact the patient, Dynabeads® show an exciting potential to improve current methods and advance healthcare as a whole.
History
In 1976 the late Professor John Ugelstad developed a process for the manufacture of polymer particles of identical size and shape. The patented technology was licensed to Dyno Particles in 1980, and lead to the development of magnetic monosized particles – the Dynabeads®. Apothekernes Laboratorium and Dyno Particles established Dynal AS in 1986 to market Dynabeads® for biomagnetic separation. In 2000 Dynal Biotech ASA acquired Dyno Particles, thereby gaining control of the entire production process.
In 2005 Dynal Biotech ASA was acquired by Invitrogen Corporation, an American company providing essential life science technologies, products and services. The Oslo site remains a centre of excellence for bead-based separations. Dynabeads® are recognized as the gold standard for biomagnetic separation. The technology is a perfect match for Invitrogen in many key application areas.
Application Areas
The magnetic magic of Dynabeads® is brought to play in a vast number of research areas. Specific ligands on the bead surface act as “bait” for the capture of target molecules, allowing simple magnetic separation of biological material (cells, nucleic acids, proteins, etc.).
Magnetic cell separation allows for studies of specific blood cells that are important to fight disease, and is also used for immunotherapy. Dynabeads® are used to isolate and detect harmful pathogens such as viruses, E.coli and Cryptosporidium. Dynabeads® also support many molecular and proteomic applications in both research and routine laboratories, as well as in in vitro diagnostics. The technology secures high sensitivity, high throughput and an unparalleled level of reproducibility.
The patented technology offers the possibility for custom-based synthesis. Dynabeads® are sold both to end-users and on an OEM basis to leading biotech, diagnostics and pharmaceutical companies.
Technology & Expertise
Dynal is known for its unique products and innovative work. The company builds R&D competence in future technologies and collaborates closely with research institutions in Europe and the United States. Dynal holds a strong portfolio of patents, intellectual property and in-licensed technology for processing and application of biological substances. The annual revenue for Dynal Bead Based Separations in 2007 was USD 53.4 million, with 10% of the total revenue devoted
to R&D.
The educational level in the company is very high. Thirty-two of its 161 employees are connected to R&D. Of the 25 employees with a Ph.D. degree, 52% are women. There are 50 research scientists and engineers, of which 66% are women.
Dynal’s high level of competence within R&D, process development and manufacturing is a very valuable asset for Invitrogen, holding ambitious targets for future growth and expansion.
