Poor B12 status as a baby was associated with a decrease in test scores at 5 years of age, reports researcher Ingrid Kvestad at Uni Research in Bergen, Norway and colleagues in a new study.
Kvestad is first author on the work, published in the American Journal of Clinical Nutrition.
– Our results clearly demonstrate associations between early vitamin B12 status and various measures on development and cognitive functioning, as for example the ability to interpret complex geometrical figures, and the ability to recognize other children`s emotions, says Kvestad.
Accordingly, the study suggests that vitamin B12 deficiency impair, or possibly delays, brain development in small children.
– The number of children in low-income countries that do not develop according to their potential is large. Our results indicate that correcting children`s vitamin B12 status early may be one measure to secure a healthy development for these vulnerable children. We are currently in the process of confirming our results in randomized controlled trials, says Kvestad.
Kvestad’s colleauge Mari Hysing at Uni Research is among the study co-authors.
The other study contributors have their affiliation at Innlandet Hospital Trust, the Tribhuvan University Teaching Hospital in Nepal, Center for Intervention Studies in Maternal and Child Health (CISMAC) at the University of Bergen, Oslo and Akershus University College, Haukeland University Hospital, Harvard T.H. Chan School of Public Health and Johns Hopkins Bloomberg School of Public Health.
In low income countries, and in particular in South Asia where many eat limited amounts of meat and other animal products, poor vitamin B12 status is prevalent. Previous findings indicate that vitamin B12 is important for the developing brain.